News

We are also currently looking to open additional sites. If your centre is interested in participating in the trial, please contact the central study team for further information and support regarding site set-up.

Dear colleagues,
We would like to thank all sites for your continued hard work and commitment. Your efforts are instrumental in helping us reach the recruitment targeted for the trial. We would like to encourage all participating sites to continue their recruitment efforts and, where possible, aim to recruit approximately 2 patients per month to support the successful delivery of the trial.

Dear colleagues,
Our next NIHR report will be submitted mid-May, and will include a site-level breakdown of recruitment up to the end of April. This reporting period provides an important opportunity for us to showcase progress across the study and recruiting 2 patients per month per site. We would especially welcome increased recruitment activity in the coming weeks, with a focus on supporting sites with lower recruitment to demonstrate measurable improvement. Mr Angelos Kolias

Dear colleagues,
Our next NIHR report will be submitted on 10 May 2026, and will include a site-level breakdown of recruitment up to the end of April. This reporting period provides an important opportunity for us to showcase progress across the study. We would especially welcome increased recruitment activity in the coming weeks, with a focus on supporting sites with lower recruitment to demonstrate measurable improvement. Mr Angelos Kolias

We would like to thank all sites for your continued hard work and commitment. Your efforts are instrumental in helping us reach the recruitment targeted for the pilot phase and in laying a strong foundation for the substantive phase. With your dedication and collaboration, we are confident that we will deliver this study to the highest standard. The trial opened to recruitment on 02 June 2025 and 118 patients have been recruited! We need at least 150 participants by December 2025 – so keep up the good work! Mr Angelos Kolias

We would like to thank all sites for your continued hard work and commitment. Your efforts are instrumental in helping us reach the recruitment targeted for the pilot phase and in laying a strong foundation for the substantive phase. With your dedication and collaboration, we are confident that we will deliver this study to the highest standard. The trial opened to recruitment on 02 June 2025 and 93 patients have been recruited! We need at least 150 participants by December 2025 – so keep up the good work! Mr Angelos Kolias

We would like to thank all sites for your continued hard work and commitment. Your efforts are instrumental in helping us reach the recruitment targeted for the pilot phase and in laying a strong foundation for the substantive phase. With your dedication and collaboration, we are confident that we will deliver this study to the highest standard. The trial opened to recruitment on 02 June 2025 and 86 patients have been recruited! We need at least 150 participants by December 2025 – so keep up the good work! Mr Angelos Kolias

TOP-TBI (CPMS ID: 61771) has now registered for Associate PI Scheme. Applicants will be able to register to be Associate PI trainees for this study from 20/06/2025 having obtained approval from their local PI.

Welcome to the first issue of the TOP-TBI Newsletter!
We would like to thank all sites for your continued hard work and commitment. Your efforts are instrumental in helping us reach the recruitment targeted for the pilot phase and in laying a strong foundation for the substantive phase. With your dedication and collaboration, we are confident that we will deliver this study to the highest standard. The trial opened to recruitment on 02 June 2025 and 60 patients have been recruited! We need at least 150 participants by December 2025 – so keep up the good work! Mr Angelos Kolias

Dear colleagues,
Welcome to the first issue of the TOP-TBI Newsletter!
We’re grateful for everyone’s hard work in screening and recruiting patients. The trial opened to recruitment on 02 June 2025 and 48 patients have been recruited! We need at least 150 participants by December 2025 – so keep up the good work! Mr Angelos Kolias